Suppositories

CBD suppositories are solid, meltable inserts designed for rectal or vaginal use. In a THC-free context, they deliver cannabidiol without measurable delta-9 THC, appealing to people who want localized application and a discreet format.

This page focuses on THC-free CBD suppositories—their makeup, general use, and practical dosing guidance. We will not cover other formats in depth; for those, see THC-Free CBD Products and the linked format guides.

Nothing here is medical advice. Everyone’s body responds differently, and you should speak with a qualified healthcare professional if you have questions about your situation.

What are CBD suppositories?

Related: which-thc-free-cbd-form-should-i-choose.

Related: which-thc-free-cbd-form-should-i-choose.

CBD suppositories are typically made with a base such as cocoa butter or polyethylene glycol (PEG) that softens at body temperature to release cannabinoids for absorption through rectal or vaginal tissues. THC-free versions use either CBD isolate or broad-spectrum hemp extract verified to have non-detectable (ND) THC on a current third-party lab report.

Formats include:

  • Rectal suppositories: Often used for localized application and systemic exposure while bypassing some digestive processes.
  • Vaginal suppositories: Used for localized application; typically inserted at night to reduce leakage.

Why choose THC-free?

People choose THC-free CBD suppositories to avoid intoxication and reduce the chance of THC exposure. “THC-free” should be supported by a Certificate of Analysis (COA) showing THC as non-detect (ND). ND does not mean absolute zero—it means THC is below the lab’s limit of quantitation (LOQ). Review the COA for:

  • Cannabinoid profile with THC reported as ND and an LOQ listed
  • Batch/lot matching your product
  • Contaminant testing (residual solvents, heavy metals, pesticides, and microbes)

Note: Even with ND THC, no product can guarantee a zero risk on drug tests. Testing sensitivity and individual factors vary; consider this before use.

Onset and duration

  • Onset: Commonly within 10–30 minutes rectally and 15–60 minutes vaginally, though timing varies by base, temperature, and individual factors.
  • Duration: Often 4–8 hours; may vary.

CBD suppository dosing

Cannabis-naïve and CBD-experienced users can respond differently. Many suppositories contain 25–100 mg CBD per unit. Consider a “start low, go slow” approach:

  • First-time use: 10–25 mg CBD per use (if your product is higher, you may be able to cut it lengthwise for a smaller portion; check firmness and hygiene before cutting).
  • Titrate: Increase by 10–20 mg per use every 1–2 uses based on comfort and response.
  • Frequency: As directed on the label, often once daily or as needed, not exceeding the manufacturer’s guidance.
  • Track: Keep notes on timing, amount, and effects to find your minimum effective amount.

If you use multiple CBD products, total your daily CBD intake to avoid inadvertently taking more than intended. For other formats, see THC-Free CBD Oil: A Complete Guide, THC-Free CBD Gummies & Edibles, THC-Free CBD Capsules & Softgels, THC-Free CBD Topicals, and THC-Free CBD Vape: Safety Guide.

How to use

  1. Read the label and review the COA to verify ND THC and quality testing.
  2. Wash hands. For easier insertion, chill the suppository briefly to firm it.
  3. Use a clean applicator or gloved finger. Optional: apply a small amount of water-based lubricant.
  4. Rectal insertion: Lie on your side and insert past the sphincter (about 2–3 cm). Remain lying for 10–20 minutes.
  5. Vaginal insertion: Insert comfortably high; consider nighttime use and a liner to manage possible leakage.
  6. Avoid immediate bowel movements or bathing to allow absorption. Store products as directed, often refrigerated.

Safety and considerations

  • Drug testing: Even THC-free products (ND on COA) cannot guarantee a negative test. Assess your risk tolerance.
  • Interactions: CBD may interact with certain medications (for example, some anticoagulants and drugs metabolized by CYP450 enzymes). Consult your clinician.
  • Sensitivities: Discontinue if irritation or discomfort occurs. Be aware of potential allergens in the base.
  • Pregnancy/breastfeeding: Discuss with a qualified healthcare professional before use.
  • Age and local laws: Follow local regulations and age restrictions.
  • Hygiene: Avoid use with active infections unless directed by a clinician.

Quality checklist (THC-free focus)

  • Hemp source and extraction method disclosed
  • Third-party COA per batch with ND THC and stated LOQ
  • Full panel testing: potency, residual solvents, heavy metals, pesticides, microbes
  • Clear labeling: CBD per unit, ingredient list, instructions, lot number, expiration date
  • Appropriate packaging and storage guidance

When suppositories may or may not make sense

CBD suppositories may be chosen for localized application or when swallowing products is undesirable. If you prefer other formats, compare options in the THC-Free CBD Products hub.

FAQ

Will THC-free CBD suppositories show up on a drug test?

No product can guarantee test outcomes. THC-free should mean ND on the COA, but ND is below the lab’s LOQ—not absolute zero. Consider your risk tolerance and policies.

How long do they take to work?

Users often report onset within 10–60 minutes depending on route and base, with effects lasting several hours. Timing varies.

Can I cut a suppository for a lower amount?

If the product is firm enough, some users carefully cut lengthwise for a smaller portion. Maintain hygiene and consistent portions; check the label for guidance.

Rectal vs. vaginal use—what’s different?

Both offer local application; absorption and comfort can vary. Vaginal use often pairs with nighttime insertion and a liner. Follow product-specific directions.

How should I store them?

Most suppositories do best in the refrigerator to maintain shape. Keep sealed, dry, and away from heat and direct light.

Shop carefully and compare COAs: If you’re ready to explore THC-free options, you can browse third-party tested products at Cannagea’s THC-Free collection.

Disclaimer: This content is for educational purposes only and is not medical or legal advice. CBD products are not intended to diagnose, treat, cure, or prevent any disease. Consult a qualified professional about your circumstances.

Summary

THC-free CBD suppositories offer a discreet, localized format. Look for ND THC verified by a recent COA with a stated LOQ, start with a low amount, and increase gradually if needed. Use hygienically, store properly, and consider medication interactions and drug-testing policies. For other THC-free formats, visit the THC-Free CBD Products hub.


Related Reading